Plasma Exchange Therapy
Boost cellular function and slow aging through plasma removal.
The benefits
Revitalize energy and cognition
Restore clarity and energy by clearing out inflammation-driving molecules that disrupt cell function.
Strengthen immune system
Boost your immune system by clearing components that add to inflammation and immune suppression, helping defend against infections and inflammatory conditions.
Slow cellular aging
Protect your cells from harmful molecules that damage DNA, hinder cell performance, and accelerate cell aging.
Is Plasma Exchange Therapy right for you?
Health considerations
Plasma exchange may help with:*
- Recovering from chronic viral infections
- Slowing progression of Alzheimer’s Disease
- Managing symptoms of autoimmune conditions
Longevity goals
Plasma exchange may help anyone seeking to:
- Live longer and free of disease
- Maintain sharp cognition and memory over time
- Prevent illness and infections
*Evidence regarding the efficacy of plasma exchange therapy in treating infections, auto-immune and neurological conditions is still emerging. More research is needed to fully understand the full scope of this treatment’s potential.
Common questions
How does Plasma Exchange Therapy work?
Here is an overview of what to expect during plasma exchange:
Step 1. Withdrawal
Your blood is withdrawn via IV.
Step 2. Plasma Separation
Your withdrawn blood is processed in a centrifuge that separates
out your plasma from other blood components (red and white
blood cells, platelets).
Step 3. Replacement
Your plasma is replaced with saline and a protein called Albumin.
Step 4. Re-Infusion
Your freshly filtered blood is re-infused via IV.
How do you separate the plasma?
After the blood is drawn, it is run through a centrifuge that separates the plasma from the other blood products.
How much does Plasma Exchange Therapy cost?
Plasma Exchange Therapy at Extension Health is administered from our West Village NYC location and costs $12,000 per session. It is not covered by insurance and is self-pay only.
Who shouldn’t get Plasma Exchange Therapy (i.e. what are some contraindications?)
People with the following conditions may not be candidates for this therapy:
–Serious heart problems
–Active infections
–Blood clotting disorders
–Severe anemia
What are some side effects of plasma exhange?
Plasma Exchange Therapy is generally safe, but some patients do experience temporary and mild side effects, including:
-fatigue
-muscle cramps
-bruising
-mild allergic reactions
-temporary drops in blood pressure
Take your health further
biological age tests
Help you assess how fast your body is really aging through:
- Analyzing inflammation
- Analyzing aging biomarkers on your DNA
Anecdotal evidence indicates that plasma exchange therapy may help to lower biological age.
longevity consultation
Collaborate with our longevity experts to build a personalized treatment plan:
- Tailored to your body’s data
- Addressing your unique longevity goals
Not sure which treatment is right for you?
Book a consult with one of our experienced team members and they will help you get started.
References
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Plasmapheresis Adjusts Inflammatory Responses in Potential Kidney Transplant Recipients.
Sadeghi M, Daniel V, Wang H, et al.
Transplantation. 2013;95(8):1021-9. doi:10.1097/TP.0b013e318286191b.
Effects of Selective H.E.L.P. LDL-apheresis on Plasma Inflammatory Markers Concentration in Severe Dyslipidemia: Implication for Anti-Inflammatory Response.
Zenti MG, Grazia ZM, Stefanutti C, Claudia S.
Cytokine. 2011;56(3):850-4. doi:10.1016/j.cyto.2011.08.038.
Metabolite-Derived Damage-Associated Molecular Patterns in Immunological Diseases.
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The FEBS Journal. 2024;291(10):2051-2067. doi:10.1111/febs.16902.
Mitochondrial DNA as Inflammatory DAMP: A Warning of an Aging Immune System?.
Zanini G, Selleri V, Lopez Domenech S, et al.
Biochemical Society Transactions. 2023;51(2):735-745. doi:10.1042/BST20221010.
The High Costs of Low-Grade Inflammation: Persistent Fatigue as a Consequence of Reduced Cellular-Energy Availability and Non-Adaptive Energy Expenditure.
Lacourt TE, Vichaya EG, Chiu GS, Dantzer R, Heijnen CJ.
Frontiers in Behavioral Neuroscience. 2018;12:78. doi:10.3389/fnbeh.2018.00078.
Acute Inflammation Alters Brain Energy Metabolism in Mice and Humans: Role in Suppressed Spontaneous Activity, Impaired Cognition, and Delirium.
Kealy J, Murray C, Griffin EW, et al.
The Journal of Neuroscience : The Official Journal of the Society for Neuroscience. 2020;40(29):5681-5696. doi:10.1523/JNEUROSCI.2876-19.2020.
Blood-Brain Barrier Disruption and Sustained Systemic Inflammation in Individuals With Long COVID-associated Cognitive Impairment.
Greene C, Connolly R, Brennan D, et al.
Nature Neuroscience. 2024;27(3):421-432. doi:10.1038/s41593-024-01576-9.
Surviving Sepsis Campaign Guidelines on the Management of Adults With Coronavirus Disease 2019 (COVID-19) in the ICU: First Update. Alhazzani W, Evans L, Alshamsi F, et al. Critical Care Medicine. 2021;49(3):e219-e234. doi:10.1097/CCM.0000000000004899.
Plasma Exchange in the Treatment of Complex COVID-19-related Critical Illness: Controversies and Perspectives. Memish ZA, Faqihi F, Alharthy A, Alqahtani SA, Karakitsos D. International Journal of Antimicrobial Agents. 2021;57(2):106273. doi:10.1016/j.ijantimicag.2020.106273.
